Dynamic light scattering method6/11/2023 ![]() ![]() b Hydrodynamic radius distribution by volume derived from intensity profiles for ND-1 at 0.4 mg/ml concentration, suggesting that volume distribution is not sensitive enough for detecting scant amount of aggregation. Degradation at 4 nm is also visible for one of the measurements in red colour. a Hydrodynamic radius distribution by intensity for nidogen-1 (ND-1) at 0.4 mg/ml, indicating that although there is a major peak for each measurement, there are multiple peaks visible between 15 nm and 500 nm ( x-axis) suggesting the presence of high molecular weight aggregated species. ![]() 6 Alberta RNA Research and Training Institute, Department of Chemistry & Biochemistry, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, T1K 3M4, Canada. 5 School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.4 Department of Biochemistry and Medical Genetics, University of Manitoba, 745 Bannatyne Avenue - Basic Medical Sciences Building, Winnipeg, Manitoba, R3E 0J9, Canada.3 Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, Manitoba, R3T 2N2, Canada. ![]() 2 Department of Biochemistry and Medical Genetics, University of Manitoba, 745 Bannatyne Avenue - Basic Medical Sciences Building, Winnipeg, Manitoba, R3E 0J9, Canada. 1 Department of Chemistry, University of Manitoba, 144 Dysart Road, Winnipeg, Manitoba, R3T 2N2, Canada. ![]()
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